Details about the upcoming Kinect game from Sega have been sparse, but the general plot was just outed by the ESRB summary as a "horror-adventure game in which players assume the role of an American tourist who must rescue his wife from a deranged scientist." The ratings-summary goes on to describe "zombie-like creatures," "disfigured monsters," and "some female creatures are depicted in revealing outfits (e.g., 'pasties' that partially cover their breasts)."
I hope that doesn't mean zombie-like breasts. That would be... upsetting.
Obviously, Rise of Nightmares has been rated M for Mature.
Source:
Joystiq