Though the original material was made for a console that really didn't have much in the way of support for special video and audio formats the game still looks as good as ever on the more capable Wii hardware. The Wii version supports both progressive scan graphics and widescreen formats for those that have the hardware to support it, and the surround sound audio is more clear and distinct on the Wii than it has ever been. In stark contrast to the PC port which avoided using any strengths of the platform, the Wii version taps into every facet of the hardware that it can. Going back to its roots on the GCN the Wii renders all cutscenes in-engine , so really other than their relative age there is nothing bad about the presentation of the game without breaking out a jeweler's lens.

The Wii version showcases all special feature campaigns from all of the previous versions from Assignment: Ada to the Special Ways campaign, both of which cast the player as the lithe Agent Ada as she uncovers other mysteries and foes on the island. The Mercenaries mode also makes an appearance which doesn't really have much in the way of a plot and is mainly an excuse for the player to get into some of the finer instances of a gun battle quickly and easily. The Wii version also has all of the alternate outfits for characters as seen on the other platforms.

The Wii edition of Resident Evil 4 is simply the best version that can be purchased on any platform. While other ports of the title have had their own share of nuances that made them not quite equal to the quality of the original, on the Wii the game simply works on a level that can easily make a newcomer think that it was always meant for that platform. The inclusion of all of the special features and unlockables from the prior versions as well as the very well thought out use of the Wiimote set the title apart, and if there is anyone left that has yet to own Resident Evil 4 –the Wii Edition is what you are looking for.